Investigators

Each and every one of our investigators is committed to advancing high-tech omics approaches and their application to biological and medical questions.

Dr Mary J. O'Connell

Dr Mary J. O'Connell

Dr. O’Connell (Steering committee for Leeds Omics) is a computational and molecular evolutionary biologist, working on the evolution of genes and genomes using large-scale data analytics. O’Connell Research Group

Dr Julie Aspden

Dr Julie Aspden

Dr Julie Aspden (Steering Committee for Leeds Omics). Julie is interested in RNA processing events of post-transcriptional gene regulation and uses RNAseq approaches (ribosome profiling, RNAseq, CLIP-seq). Aspden Research Group

Dr Niamh Forde

Dr Niamh Forde

Dr Niamh Forde (Steering committee for Leeds Omics). Dr Forde’s group investigate the molecular mechanisms required for establishing and maintaining a successful pregnancy.

Dr Ian Carr

Dr Ian Carr

Dr Ian Carr is a medical bioinformatician and the academic lead at the Next Generation Sequencing facility – a partnership between University of Leeds and Leeds Teaching hospitals. Full profile

Professor Jenny Barrett

Professor Jenny Barrett

I am a biostatistician with research interests primarily in the analysis of genetic/genomic data in relation to disease risk, outcome and response to treatment, working mainly in cancer and musculoskeletal disease. Full profile

Professor David J Beech

Professor David J Beech

Calcium entry and non-selective cationic channels in vascular physiology and disease. Full profile

Dr Amanda Bretman

Dr Amanda Bretman

Dr Bretman’s group work on the area of behavioural ecology from a molecular perspective incorporating transcriptomic approaches to address fundamental questions about sexual selection. Full profile

Dr Suparna Mitra

Dr Suparna Mitra

Dr Suparna Mitra is a University Academic Fellow in Gastrointestinal Research including Bioinformatics. She works within the Healthcare Associated Infection Research Group, using bioinformatics approaches to understand microbiome sequencing samples.

Dr Edwin Chen

Dr Edwin Chen

Dr Chen’s group work to understand the molecular pathways that control the clonal evolution of leukaemic stem cells in human haematological malignancies, with a specific focus on aberrant JAK/STAT signalling. Full profile

Dr Ron Chen

Dr Ron Chen

Dr Chen’s group work in the area of functional genetics and genomics, chromatin structure and epigenetic control in gene expression. The Chen Lab of Chromatin Biology

Dr Richard Cubbon

Dr Richard Cubbon

My group is interested in understanding how diabetes and pre diabetes cause vascular disease and interfere with endogenous vascular regeneration. Full profile

Professor Jim Deuchars

Professor Jim Deuchars

The properties of the neuronal circuitry that controls the cardiovascular system and how they might be harnessed for patient benefit in cardiovascular disease. Full profile

Dr Elizabeth Duncan

Dr Elizabeth Duncan

My reseach interests are evolution of eusociality, phenotypic plasticity, invertebrate developmental biology, evolution of developmental pathways, genome architecture and evolution. Full profile

Dr Katie Field

Dr Katie Field

Dr Field (BBSRC Translational Fellow) and her group work on ecophysiology, plant-fungal symbioses and environmental metabolomics for agronomic benefit such as enhanced crop access to existing soil P pools. Full profile

Dr Simon Goodman

Dr Simon Goodman

Dr Goodman’s group use genomic and transcriptomic technologies to investigate how patterns of genetic variation relate to disease susceptibility, and the mechanisms by which disease acts as major conservation threat. Full profile

Dr Mark Iles

Dr Mark Iles

The epidemiological analysis of population-based omics data to understand disease aetiology, disease progression and treatment response. Full profile

Professor J. Bernadette Moore

Professor J. Bernadette Moore

Application of proteomic and systems biology approaches to understanding fatty liver disease, obesity and other questions within the Nutritional Sciences. Full profile

Professor Ian Hope

Professor Ian Hope

Prof. Hope (Head of School of Biology) works on developmental gene expression pattern genomics of Caenorhabditis elegans. Prof. Hope’s Group

Professor David Westhead

Professor David Westhead

We analyse omics data to gain understanding of biological mechanisms with applications in cancer classification. Full profile

Dr Andrew Cuming

Dr Andrew Cuming

Interested in: (i) The evolution of gene function and adaptations to colonisation of terrestrial habitats; (ii) Molecular mechanisms underpinning homology-dependent transgene integration (“gene targeting”) in P. patens Dr Cuming’s Group

Professor Kenny McDowall

Professor Kenny McDowall

Studies the biological significance of structure-function studies on the machinery of gene expression, identifying new phenomena within bacterial systems renowned for benefiting human health and wellbeing. Prof. McDowall’s Group

Professor Roz Banks

Professor Roz Banks

Clinical proteomics approaches for biomarker discovery, mechanistic insights and novel therapeutic targeting. We also provide a local research facility service for proteomics analysis. Prof. Bank’s Group

Professor Adrian Whitehouse

Professor Adrian Whitehouse

Omic approaches to globally identify how human tumour viruses affect the host cell environment. Full profile

Dr Ian Wood

Dr Ian Wood

Epigenetic modifications and the regulation of gene expression in chronic disease states. Full profileNeur@l: Neuroscience Research at leeds

Dr Paolo Actis

Dr Paolo Actis

Dr Actis is a University Academic Fellow in the School of Electronic and Electrical Engineering. His group aims to develop an electrical nanobiopsy platform capable of extracting genetic material and organelles from single living cells. Full profile here.

Dr Lucy Stead

Dr Lucy Stead

Dr Stead’s group investigates intratumour heterogeneity in GBM; specifically testing whether treatment-resistant subclones emerge in recurrent tumours, and characterising them in clinically relevant ways in multiple patients. Dr Stead’s Group.

Dr Arief Gusnanto

Dr Arief Gusnanto

My research interest is in the development of statistical methods and inference in the analysis of omics data. Dr Gustnanto’s website.

Dr Susan A. Deuchars

Dr Susan A. Deuchars

Dr Deuchars Group study how cells within the spinal cord fit into complex and specialised neuronal circuits, with a special interest in whether newly born cells in the adult spinal cord can integrate into these circuits.
Dr Andrew Tuplin

Dr Andrew Tuplin

Dr Tuplin’s research is focused on investigating how RNA viruses control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA.
Dr Christopher Hassall

Dr Christopher Hassall

Dr Hassall’s research group studies a wide range of ecological and evolutionary phenomena including ageing, camouflage, mimicry, dispersal, thermal biology, urbanisation, and climate change, using molecular, lab, and field study systems. Leeds Profile.

Professor Glenn McConkey

Professor Glenn McConkey

Prof. Mc Conkey researches physiological changes caused by environmental factors (protozoan parasites) in disease using genomic metabolic networks, genomic data, software design and epigenomics. Prof. Mc Conkey’s Group.

Dr Reuben Tooze

Dr Reuben Tooze

Dr Tooze’s Group utilises omics approaches to explore the mechanism and process of human plasma cell differentiation and the relationship to B-cell malignancies.
Dr Henry Greathead

Dr Henry Greathead

Dr Greathead’s research is in the study of rumen microbiome of cattle and the digestion of high fibre diets. Full profile.

Dr Hannah Dugdale

Dr Hannah Dugdale

Dr Dugdale’s group studies within- and between-individual differences in behavioural and life-history traits in natural populations, to understand why diversity in traits evolved and is maintained.

Professor Jeanine Houwing-Duistermaat

Professor Jeanine Houwing-Duistermaat

Professor of Data Analytics and Statistics at Leeds, interested in the development of methodology for integrated analysis of multiple omics datasets and joint modelling of one type of omics data from different platforms (harmonization). Professor Houwing-Duistermaat’s Group. 

Dr. Patricija van Oosten-Hawle

Dr. Patricija van Oosten-Hawle

Research in the van Oosten-Hawle lab aims to understand how cellular stress responses are communicated across different tissues within the complexity of an entire organism; and how this can be harnessed for the treatment of age-dependent neurodegenerative protein diseases. See more on our lab website

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