Each and every one of our investigators is committed to advancing high-tech omics approaches and their application to biological and medical questions.
Dr Julie Aspden
Dr Julie Aspden (Steering Committee for Leeds Omics). Julie is interested in RNA processing events of post-transcriptional gene regulation and uses RNAseq approaches (ribosome profiling, RNAseq, CLIP-seq). Aspden Research Group
Dr Niamh Forde
Dr Niamh Forde (Steering committee for Leeds Omics). Dr Forde’s group investigate the molecular mechanisms required for establishing and maintaining a successful pregnancy.
Professor Colin A Johnson
My research uses functional genomics and transcriptomics to investigate the roles of primary cilia in health and disease. Currently, my group is investigating the links between primary cilia, pre-mRNA splicing factors and inherited retinal disorders using cellular model systems. Full profile
Dr Ian Carr
Dr Ian Carr is a medical bioinformatician and the academic lead at the Next Generation Sequencing facility – a partnership between University of Leeds and Leeds Teaching hospitals. Full profile
Professor Jenny Barrett
I am a biostatistician with research interests primarily in the analysis of genetic/genomic data in relation to disease risk, outcome and response to treatment, working mainly in cancer and musculoskeletal disease. Full profile
Dr Amanda Bretman
Dr Bretman’s group work on the area of behavioural ecology from a molecular perspective incorporating transcriptomic approaches to address fundamental questions about sexual selection. Full profile
Dr Caroline Chilton
Caroline is a microbiologist who’s research focuses on Healthcare Associated Infections. She is particularly interested in the use of omics technologies to investigate the composition and function of the gut microbiota, how the microbiota interacts with potential pathogens, and how these interactions are influenced by antibiotic exposure. Full profile
Dr Elizabeth Duncan
My reseach interests are evolution of eusociality, phenotypic plasticity, invertebrate developmental biology, evolution of developmental pathways, genome architecture and evolution. Full profile
Dr Simon Goodman
Dr Goodman’s group use genomic and transcriptomic technologies to investigate how patterns of genetic variation relate to disease susceptibility, and the mechanisms by which disease acts as major conservation threat. Full profile
Dr Andrew Cuming
Interested in: (i) The evolution of gene function and adaptations to colonisation of terrestrial habitats; (ii) Molecular mechanisms underpinning homology-dependent transgene integration (“gene targeting”) in P. patens Dr Cuming’s Group
Professor Kenny McDowall
Studies the biological significance of structure-function studies on the machinery of gene expression, identifying new phenomena within bacterial systems renowned for benefiting human health and wellbeing. Prof. McDowall’s Group
Dr Paolo Actis
Dr Actis is a University Academic Fellow in the School of Electronic and Electrical Engineering. His group aims to develop an electrical nanobiopsy platform capable of extracting genetic material and organelles from single living cells. Full profile here.
Dr Lucy Stead
Dr Stead’s group investigates intratumour heterogeneity in GBM; specifically testing whether treatment-resistant subclones emerge in recurrent tumours, and characterising them in clinically relevant ways in multiple patients. Dr Stead’s Group.
Dr Arief Gusnanto
My research interest is in the development of statistical methods and inference in the analysis of omics data. Dr Gustnanto’s website.
Dr Susan A. Deuchars
Dr Andrew Tuplin
Professor Glenn McConkey
Prof. Mc Conkey researches physiological changes caused by environmental factors (protozoan parasites) in disease using genomic metabolic networks, genomic data, software design and epigenomics. Prof. Mc Conkey’s Group.
Professor Jeanine Houwing-Duistermaat
Professor of Data Analytics and Statistics at Leeds, interested in the development of methodology for integrated analysis of multiple omics datasets and joint modelling of one type of omics data from different platforms (harmonization). Professor Houwing-Duistermaat’s Group.
Dr. Patricija van Oosten-Hawle
Research in the van Oosten-Hawle lab aims to understand how cellular stress responses are communicated across different tissues within the complexity of an entire organism; and how this can be harnessed for the treatment of age-dependent neurodegenerative protein diseases. See more on our lab website
Dr Megan Wright
Dr Megan Wright is a chemical biologist developing and applying chemical tools in combination with proteomics to interrogate protein function and modification in live cells. Profile link.
Dr Stefan Kepinski
Stefan is a plant biologist working on the regulation of plant development by the hormone auxin. Projects range from the structural biology of auxin perception to the molecular and genetic basis of root and shoot architectural control. His interest in omics technologies are principally in whole genome resequencing for the identification of causal mutations from forward genetic screens and in single cell/cell-type-specific RNA Seq. Full profile
Dr Viktor Lukacs
Dr. Lukacs’ lab is interested in the molecular underpinning of somatosensation. His research focuses on new techniques in functional genomics (including tools of genome-editing such as CRISPR) to identify new receptors and regulatory proteins in the pain pathway. Full profile